近十年模拟移动床色谱在药物领域应用的文献分析

A Survey of Literatures on Simulated Moving Bed Chromatography Applied in Field of Pharmaceuticals for Last Ten Years

模拟移动床色谱 (SMBC)技术在药物领域应用始于 2 0世纪 90年代 .前期主要是理论性探索和实验室的初步试验 ;中期 ,进展到实验室药物分离条件最优化和优化理论模型及经验公式的程度 ;现在 。

The application of simulated moving bed chromatography(SMBC) technology in the field of pharmaceuticals began in the early 90s 20th.In the first stage,its theoretical studies and basic laboratory experiments were carried out;in the second stage,the pharmaceutical_separating conditions were optimized,and the optimization theory models and empirical formulas were set up;and now the separated quantity by using this technology has reached kilogram or even ton levels.