白细胞与蛛网膜下腔出血216例分析

White blood cells and subarrachnoid hemorrhage: Analysis of 216 cases/

分析216例蛛网膜下腔出血(SAH)发病48h内WBC变化与病情轻重及预后之间关系。发现WBC增高占55.1％(119/216例),降低仅1例;中性粒细胞增高占83.3％(180/216例)。嗜酸粒细胞减少或消失占79.6％(172/216)。WBC增多与SAH的病情及预后密切相关(P<0.01),当WBC>16.0×10~9/L,预后明显不良,WBC越高,病情越重,预后越差;中性粒细胞增高预后也不良;嗜酸粒细胞增高或正常者病情轻,预后好,减少或消失者恶化率及病死率明显增高。作者就SAH致WBC改变的机理及相互影响进行了讨论。

The relationship between the change of white blood cells (WBC) within 48 hours after subarrachnoid hemorrhage (SAH) and the severity and prognosis of the disease was analyzed in 216 cases. 119 of the patients (55.1%) were found to have increased WBCs; only one patient＇s WBC was decreased. Increased neutrophils aceounted for 83.3% of the patients (180/216). Decrease or absence of eosinophils were seen in 79. 6% of the patients (172/216). Increase of WBC was closely correlated with the severity and proghosis of SAH (P<0. 01). The prognosis was obviously poor when WBC was> 16.0×10~9/ L. The higher the level of WBC, the severer the state of illness, and the poorer the prognosis. In- creased neutropsils were also an omnious sign of SAH. Increased or normal eosinophils suggested a mild SAH with a good prognosis, The mortality rate was high when cosinophil was decreased or disappeared.