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环氧酶抑制剂消炎痛对严重脑外伤治疗作用的研究进展 被引量:1

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摘要 严重脑外伤后可引起全身及颅内一系列病理生理和生物化学的紊乱,伤后颅内压(ICP)增高是脑外伤急性期治疗的一个关键环节,而控制这类ICP增高,有时甘露醇等脱水剂难以奏效。过度换气。
作者 张赛 杨卫东
出处 《中国危重病急救医学》 CAS CSCD 1993年第5期312-314,共3页 Chinese Critical Care Medicine
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  • 1李志强,张永亮,李灵芝,舒清明.环氧化酶-2在闭合性颅脑损伤中的表达[J].武警医学,2006,17(8):570-573. 被引量:1
  • 2Tofteng F.The effect of indomethacin on intracranial pressure,cerebral perfusion and extracellular lactate and glutamate concentrations in patients with TBI.J Cereb Blood Flow Metab,2004,24(7):798
  • 3Rasmussen M.Treatment of elevated intracranial pressure with indomethacin:friend or foe? Acta Anaesthesiol Scand,2005,49(10):1577
  • 4Hean Z,Sokhon P.Regulation of Heme Oxygenase Expression by Cyclopentenone Prostaglandins.Experimental Biology and Medicine,2003,228(5):499
  • 5Jensen K.The effects of indomethacin on intracranial pressure,cerebral blood flow and cerebral metabolism in patients with severe head intracranial hypertension.Acta Neurochir,1991,91(08):116
  • 6Burkey THK,Regan JW.Activation of m itogenactivated proteinkinase by the human prostaglandin EPA receptor.Biochem Biophys,1995,211(3):152
  • 7TAN ZG.Influence of indomethacin on free radical reactions in brain tissues of rabbits with brain injury.Journal of Henan Medical University,2001,36 (1):48
  • 8Baranovd.Armstead wm.prostaglanding contribute to impared angio-tensin Ⅱ-induced cerebral vasodilation after brain injury.J Neurosurg,2002,19(11):318
  • 9Heinert G,Nye PC,Paterson DJ.Nitric oxide and prostaglandin pathways interact in the regulation of hypercapnic cerebral vasodilatation.Acta Physiol Scand,1999,166 (3):183
  • 10Tong H,Wood CE.Indomethacin attenuates the cerebral blood flow response to hypotension in late gestation fetal sheep.Am J Physiol,1999,277 (52):1268

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