摘要
本文用气相色谱法测定75例慢性肝炎及肝硬化患者血清游离脂肪酸组分变化。结果,慢性肝炎、肝硬化患者血清饱和脂肪酸和单价不饱和脂肪酸增多,而多价不饱和脂肪酸(亚油酸和花生四烯酸)含量则显著降低。不饱和脂肪酸/饱和脂肪酸比值在肝硬化组(51例)为1.84±0.2,明显低于正常人组2.22±0.27(P<0.001)。其发生机制及其临床意义尚不十分明显。
The Changes of the serum fatty acid composition in 75 Patients with chroniehepatitis and liver cirrhosis were determined by gas chromatography. The results showed that the multiunsaturatified fatty acids (linoleic acid and arachidonic acid) were markedly decreased in these diseases. The unsaturated/saturated fatty acid ratio 1.84±0.2 in liver cirrhosis (51 cases) was obviously lower than that of control group (2.22±0.27, P<0.001). The mechanism and the clinical significance were briefly discussed.
出处
《上海第二医科大学学报》
CSCD
1989年第4期299-301,共3页
Acta Universitatis Medicinalis Secondae Shanghai
关键词
血清脂肪酸
肝炎
肝硬变
fatty acid composition chronic hepatitis liver cirrhosis
