摘要
本实验选用 2 0头 6 0dSPF小型猪 ,雌雄各半 ,对其 2 6项血液常规、生化正常值和 18项尿常规值进行测定 ,并将雌雄SPF小型猪血液常规、生化常值、尿常规值进行比较。结果表明 :SPF小型猪血、尿值变动幅度更小 ,SPF小型猪血液成分变化趋势与文献报道SPF大、小鼠血液成分变化趋势一致 ,红细胞 (RBC)总数、血红蛋白 (Hgb)量较高 ,白细胞 (WBC)总数、中性粒细胞 (NEUTRO)较低。淋巴细胞 (LYM)、中性粒细胞分叶型 (NEUTROl)、血清球蛋白 (GLOb)、白球比 (ABG)相差非常显著 (P <0 0 1) ;淋巴细胞、白球比雌性高于雄性 ,中性粒细胞分叶型、血清球蛋白雄性高于雌性 ;血小板总数 (PLT)、酸性粒细胞 (EO)、血液pH值 (pH)、血清白蛋白 (ALB)、血清氯 (Cl)、血清钠(Na)、血清钙 (Ca)、血清磷 (P)相差显著 (p <0 0 5 ) ;血液pH值、血清白蛋白、血清钙、血清磷雌性高于雄性 ;血小板总数、酸性粒细胞、血清氯、血清钠雄性高于雌性 ;其他血液常规、生化常值及 18项尿常规值 ,雌雄SPF小型猪相差不显著 (p >0 0 5 )。
In this experiment we selected 60 day old SPF miniature pigs, the male and female were all 10, to measure the 26 clinical normal values of hematology and serum biochemistry, the 18 clinical normal values of urine and make contrast analysis between the male and female. The results showed that the variation trend of SPF miniature pi g blood ingredients was in conformit y to blood variation trend of SPF mouse and SPF rat, RBC and Hgb higher, WBC and NEUTRO lower. LYM, NEUTROl, GLOb,ABG of the male and female had very significan t difference ( P <0.01),LYM and ABG of the female were higher than the male's, NEUTROl and GIOb of the male were higher than the female's . PLT,EO ,pH,A LB,Cl,Na,Ca,P had significant difference ( P <0.05), pH,ALB,Ca,P of the female were higher than the male's, PLT,EO,Cl,Na of the male higher than the female's . The other blood ingredients and 18 clinical normal values of urine had no diffe rence ( P >0.05).
出处
《中国实验动物学杂志》
2001年第3期134-137,共4页
Chinese Journal of Laboratory Animal Science
基金
广州军区广州总医院科研基金资助
