紫绀型先天性心脏病高粘滞血症的血液稀释治疗

HEMODILUTION IN PATIENTS WITH HYPERVISCOSAEMIA SECONDARY TO CYANOTIC CONGENITAL HEART DISEASE

青紫型先天性心脏病高粘滞血症患儿23例,采用等容量血液稀释治疗。在心导管术中放血,同时注入等量6%低分子右旋糖酐,剂量按10 ml·kg^(-1)/次计算。血液稀释治疗后患儿临床表现好转,血液粘度降低,左心功能。甲襞微循环均改善,为外科手术做好术前准备。

Isovolumic hemodilution was performed in 23 children with hyperviscosaemia secondary to cyanotic congenital heart disease. During catheterization, 10 ml/kg of body weight of blood was removed and replaced by 6% dextran 40. After treatment, blood viscosity was reduced, Clinical manifestation, left ventricular function and nailfold microcirculation were improved. The data show that it is worthwhile to perform isovolumic hemodilution in these patients as a preoperative measure.