摘要
在生产中发现盐酸丁卡因有2个熔点:一个为147.5～149℃,另一个为135～136℃,经化学分析法、核磁共振、红外光谱和x光粉末衍射等方法的测定,证明2个不同熔点的盐酸丁卡因是同质异晶体。这2个不同熔点的盐酸丁卡因亦可转换同一游离碱。
Some properties of tetracaine hydrochloridewere investigated by X-ray diffraction, IR, HNMRand chemical analysis method. Two different crys-tal forms were found: high melting form (mp147.5～149℃)and low melting form(mp135～136℃). The two forms were polymorphous sub-stances and could be transformed into the same base(mp42～43℃).
出处
《中国药学杂志》
CAS
CSCD
北大核心
1993年第1期33-34,共2页
Chinese Pharmaceutical Journal
关键词
盐酸丁卡因
化学分析
tetracine
polymorphism
analysis
