104例胃癌功能分化与组织学分化的比较研究——利用酶组化、粘液组化方法

Comparative Study on the Functional and Morphological Differentiations of 104 Human Stomach Cancer Using Enzyme-and Mucin-Histochemical Methods

本文采用酶组织化学和粘液组织化学方法,对104例胃癌的功能分化状态进行了系统观察。根据组化功能检测结果,将本组胃癌分为五个功能分化类型:1.吸收功能分化型;2.粘液分泌功能分化型;3.吸收—粘液分泌功能双向分化型;4.特殊功能分化型;5.无功能分化型。研究结果表明:相同组织学类型的胃癌具有不尽相同的功能分化特征;不同功能分化的胃癌具有不同的浸润扩散能力。结果提示:单纯形态学描述在反映胃癌的生物学特征方面有一定的局限性。有必要增加功能分化的信息以弥补其不足。

Functional differentiations of 104 human stomach cancer specimens were studied by enzyme and mucin-histochemical methods. According to the results of the investigation, these stomach cancers were divided into five different functionally differentiated types: absorptive-function differentiated type; mucin-producing-function differentiated type; absorptive and mucin-producing-function differentiated type; non-function differentiated type and special-function differentiated type. The results showed that different functionally differentiated types of the stomach cancer possessed different rules of infiltration and metastasis. The relationship between the functional differentions and rules of infiltration and metastasis of stomach cancer cells was discussed.