益气活血法治疗慢性肺源性心脏病低氧血症的临床研究

A Clinical Research on Treating Hypoxemia of Chronic Pulmonary Heart with the Method of Replenishing Qi and Promoting Blood Circulation

应用益气活血法,静滴参麦注射液及丹参注射液治疗47例慢性肺心病低氧血症患者,并以同期具有可比性的25例非益气活血法治疗的患者作对照。临床结果表明,益气活血法能显著提高PaO_2、SaO_2及2、3-DPG水平,从而起到改善肺心病低氧血症的作用;同时,结合血液流变学及免疫等指标的变化,初步认为其作用机理可能与改善肺通气功能、降低血粘度、调整通气/血流比例及提高机体的防御作用等因素有关。

Adopting the method of replenishing qi and promoting blood circulation, 47 cases of hypoxemia of chronic pulmonary heart disease were driped intravenously with ShenMai injection and Danshen injection. The Control group had 25 cases who were not treated with the same method but could be comparied because of in the same disease stage. The clinical results showed that the method of replenishing qi and promoting blood circulation could remarkedly increase the levels of PaO_2, SaO_2 and 2, 3-DPG , so as to play the role of improving hypoxemia of pulmonary heart disease. Combining with the index changes of blood theology and immunology, it was thought preliminarily that its mechanism of action might be related to some factors such as improving pulmonary ventilation, reducing blood viscosity, regulating the proportion of ventilation and blood flow,and increasing the body's defense functions, etc.