小儿庆大霉素的血药浓度分析及与尿β_2—MG的关系

The analysis of pediatric gentamycin blood concentration and the study of relationship with β_2-MG in the urine

本文比较了静脉血和指血中庆大霉素的浓度,结果二者有显著的正相关。另外动态地监测庆大霉素血药浓度及其与尿β_2-MG 的相关性。结果表明:用指血测定庆大霉素血药浓度是可行的,对早期发现预测其肾毒性指导儿科用药具有重要意义。

Gentamycin concentration in the periphery blood and finger blood were determined simuitanously.There was a positiverelationship as a straight line.The gentamycin blood concentration and β_2-MG in the urine were determined regularily,itshowed the possibility of determining gentamycin concentration with finger blood.It had important significance for the earlyrecognition of nephritic toxicity and pediatric clinical use of gentamycin.