拉萨高原居民肺容量的测定

DETERMINATION OF LUNG CAPACITY IN TIBETAN HIGH ALTITUDE RESIDENTS

对年龄、身高和体重相同的拉萨男性世居藏族39人和男性移居汉族43人的肺容量进行了测定。结果显示:藏族组的肺活量(VC)、肺总容量、胸围均大于汉族组,残气量有大于汉族组之趋势(P=0.06)。胸围的大小与VC呈正相关。5岁前和18岁后移居高原者之肺容量无差别。结果提示,拉萨世居藏族具有较大的肺容量,这对提高肺弥散功能和维持运动时的血氧饱和度有重要意义。

Increased chest dimension and lung capacity in relation to human adaptation to high altitude have been reported. To determine if high altitude Himalayans (Tibetans) had larger lung capacity than acclimatized Han newcomers, we studied 39 Tibetan and 43 Han residents of Lhasa, China, (elevation 3658m)matched for age, height, weight and smoking history. The Tibetans presented larger VC, TLC and chest circumference than the Hans, and the chest circumference was positively correlated with VC within each group. Hans who had migrated to high altitude as children (< 5 years old, n = 6) and adults (> 18 years old, n = 26) were similar in lung capacity. The Tebitan VC and TLC in relation to body size were similar to values of lifelong residents of high altitude in South and North America. A large lung capacity may be important for raising lung diffusion capacity and preserving arterial O2 saturation during exercise at high altitude.