丹参对腹膜透析效能的影响

Effect of Injection Salvia mlltiorrhizae on Peritoneal Dialysis

将丹参注射液加至腹膜透析液中,观察其对腹膜透析效能的影响,并与单纯腹透液组及多巴胺组对照比较。结果发现,丹参能显著提高腹膜对血肌酐、尿素氮、尿酸的清除率和超滤量。同时,通过三种不同浓度丹参(4‰、6‰、8‰)的组间比较,浓度以6‰疗效最好。

Effective volume of blood flow of peritoneal capillary is an important factor influencing theeffciency of peritoneal dialysis. Injection of Salvia miltiorrhizae(ISM) could dilate the blood vesselsand improve microcirculation. The effect of peritoneal dialysis with three kinds of dialytic fluid wasstudied. The dialysate of first group contained ISM, the second used dialysate only, the thirdcontained dopamine. The result found that ISM could markedly increase the clearance rate andultrafiltration rate of the peritoneum to creatinine, urea nitrogen and uric acid. Three concentra-tions of ISM (4%, 6%, 8%) were also compared. This comparison showed that 6% injection of ISMwas the optimal concentration.