164例肾炎患者血液流变学指标及其与血瘀证的关系

Observation of Hemorheology and Blood stasis in 164 Cases of Nephritis

本研究观察了164例肾炎患者血液流变学指标及其与血瘀证的关系。结果肾炎患者血液流变学(含血凝指标)检测值多显著高于正常对照组(P<0.05～0.01),并随病情恶化而显著加重(P<0.05～0.01)。血液高粘滞综合征(BHS)和血瘀证发生率,也随病情恶化而显著增加(P<0.05～0.01)。BHS分组与血瘀证分度、血凝指标与病变严重性均呈正相关。结果提示:BHS是血瘀证重要病理基础之一;BHS和血瘀证是肾炎病变恶化的一个重要原因。

The criteria of nephritic patients' hemorheology (including blood, coagulative indicis) were higher than those of the control group (P< 0.05-0.01), and following the aggravation of the illness,it deteriorated significantly (P< 0.05-0.01). Blood hyperviscosity syndrome (BHS) and the incidence of Blood Stasis also increased markedly (P< 0.05-0.01). The classification of BHS and graduation of Blood Stasis, blood coagulative indicis and the severity of the disease were interrelated positively.Results showed that BHS (especially the hyperviscosity state) was the important athologic basis in the pathogenesis of Blood Stasis Syndrome. BHS and the Blood Stasis Syndrome were the main causes of the aggravation of nephritis.