放射性胶体^(198)Au治疗晚期肺癌胸腔积液的临床观察

Treatment of Pleural Effusion Associated with Lung Cancer Using Colloid^(198)Au Intrapleural Instillation

本文20例肺癌晚期胸腔积液病人,经胸腔注入放射性胶体^(198)Au35～50mCi,与20例未经胸腔内治疗的肺癌晚期胸腔积液病人进行对照临床观察,两组疗效差异显著(P<0.05)。其治疗组完全缓解率40％,部分缓解率60％。提高了病人的中位生存期。

Twenty patients with pleural effusion in association with lung cancer were treated by intratho- racic instillation of radioactive colloid ^(198)Au in a dosage of 35-50 mCi. As control,another 20 patients with the same disease did not receive this agent. Results of these two groups of patients were compared and significant differences have been found(P<0.05). In the treated group,complete remission was achieved in 40 per cent of patients and partial remis- sion in 60 per cent. The median survival period of this group was longer than that of the control group.