大肠乳头状肿瘤AgNOR的观察与探讨

Studies on Argyrophilic Proteins of the Nucleolar Organizer Region(AgNOR)in Papillomatous Tumors of Large Bowel

对87例大肠乳头状肿瘤(腺瘤19例,腺瘤伴不典型增生8例,腺癌60例)行核仁组成区相关嗜银蛋白(AgNOR)观察分析。提示,AgNOR随细胞增生的程度而增加,在良恶性病变之间有显著差异(P<0.001)。因此,对病理学诊断和科研为一有用手段。

The significance of AgNOR in pepillomatous tumors of large bowel was assessed. of the tumors stud- ied 60 were adenocarcinoma, 19 adenoma, and 8 adenoma associated with atypical hyperplasia. The results showed that AgNOR level was elevated with the increase of cellular proliferation, and that there was significant difference (P<0.001) between benign and malignant tumor. It is concluded that AgNOR test is an useful tool in pathologic diagnosis and research as well.