38例肝豆状核变性的肝肾声像图研究

Ultrasonography of the Liver and Kidney in Hepatolenticular Disease (A Study of 38 Cases)

本文报告38例肝豆状核变性(HLD)的肝肾声像图观察结果。肝实质声像图可分为光点闪烁型(8例)、岩层征型(14例)、树枝状光带型(5例)和结节型(11例)。光点闪烁型、岩层征型是HLD肝硬化前期肝损害较轻声像图特征;而结节型为前三型病情渐进发展的结果,属HLD肝硬化晚期改变的声像图表现。33例(33/38)肾皮质内光点增多、增粗、增强或呈小光斑回声。本文资料提示不同类型特征的声像图与病程发展的不同阶段有关,反映了HLD铜沉积由轻到重的病理过程,为HLD的诊断、鉴别诊断和了解病情发展提供一种形态学改变特征的无创性新技术。

The liver and kidney were examined with ultrasonography in 38 cases of hepatolenticular disease (HLD). The sonograms of the liver were classified into four types : i. e. glinting echogenic dots type (8 cases), rock stratum type (14 cases), tree—like type (5 cases) and nodular type (11 cases), The first tow types represented the ultrasonographic feature of the mildly damaged liver in the precirrhotic stage, whereas the fourth type was the development of the former three types and represented the final result of the advanced cirrhotic stage. The sonograms of the kidney showed increased numbers and brightness of echoes of the cortex in 33 cases (33/38). It was considered that the different types of the hepatic sonograms were related to the different stages of the pathological processes and demonstrated the changes resulting from copper accumulation from mild to severe degree. It is concluded that ultrasonography is a new noninvasive technique for the diagnosis and differentiation of HLD and a useful means to follow the course of disease.