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肺癌增殖细胞核抗原的表达与核仁组成区比较研究 被引量:3

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摘要 用肺癌增殖细胞核抗原(PCNA)免疫组化和核仁组成区(AgNOR)胶银染色法对比观察了73例肺癌。PCNA标记指数(LI)和AgNOR计数可较敏感地反映细胞增殖活性,其数量变化与肺癌组织学分级有关,每核AgNOR平均量与PCNA标记指数呈显著性正相(r=0.70,P<0.01)。结果提示,这两种细胞增殖的检测指标可作为肺癌分级诊断的参数。
作者 赵彤 张亚历
出处 《中华结核和呼吸杂志》 CAS CSCD 北大核心 1993年第6期342-344,共3页 Chinese Journal of Tuberculosis and Respiratory Diseases
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参考文献2

  • 1赵彤,癌症,1992年,11卷,270页
  • 2钱翔,国外医学生理病理科学与临床分册,1991年,11卷,198页

同被引文献13

  • 1许良中.关于核仁组成区研究工作的标准化方案[J].中华肿瘤杂志,1993,15(5):380-380.
  • 2金丕焕.医学统计学方法[M].上海:上海医科大学出版社,1993.90.
  • 3Underwood JCE,Giri DD.Nucleolar organizer regions as diagnostic discrimination formalignancy.J Pathol,1988;155(2):95-96
  • 4Ploton D,Menager M,Jeannesson P,et al.Improvement in the staining and in thevisualization of the argyrophilic proteins of the nucleolar organizer region of theargyrophilic proteins of the nucleolar organizer gegion at the optical level.HistochemJ,1986;18(1):5-14
  • 5Crocker J,Nar P.Nucleolar organizer regions in lymphomas.JPathol,1987;151(2):111-118
  • 6Huang MS,Tsai MS.Hwang JJ et al.Comparison of nucleolar organiser regions and DNAflow cytometry in the evaluation of pleural effusion.Thorax,1994;49(11):1152-1156
  • 7Schwarzacher RT,Kraemer PM,Cram LS.Spontaneous in vitro neoplastic evolution ofcultured chinese hamster cells.Nucleolus organizing region activity.Cancer GenetCytogenet,1988;35(1):119-128
  • 8Ploton D,Menager M,Jeannesson P,et al.Improvement in the staining and in the visualization of the argyrophilic proteins of the nucleolar organizer region at the optical level.Histochem J,1986,18(1):5-14
  • 9Underwood JCE,Giri DD.Nucleolar organizer regions as diagnostic discrimination for malignancy.J Pathol,1988,155(2):95-96
  • 10Huang MS,Tsai MS,Hwang JJ,et al.Comparison of nucleolar organiser regions and DNA flow cytometry in the evaluation of pleural effusion.Thorax,1994,49(11):1152-1156

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