苯系混合物对女工妊娠经过及妊娠结局影响的研究

THE EFFECTS OF MIXTURE OF BENZENE.TOLUENE AND XYLENE ON PREGNANCY COMPLICATION AND OUTCOME OF FEMALE WORKERS

对接触苯系混合物的女工737人及对照女工1251人的妊娠经过及妊娠结局进行了调查,应用回顾性队列研究方法。结果表明,孕期接触苯系混合物女工的妊娠剧吐、妊高征、妊娠期贫血、自然流产及低出生体重发生率明显高于对照组。Logistic回归分析表明,妊高征、妊娠期贫血、自然流产、低出生体重的发生主要与接触苯系混合物有关联,与妊娠年龄、妊娠时被动吸烟等因素无关。接触组女工所在车间空气中苯、甲苯、二甲苯的年平均浓度接近或超过国家卫生标准1～2倍。

The adverse pregnancy complications and outcomes of 737 female workers occupationally exposed to the mixture of benzene,toluene and xylene and 1251 controls were studied retrospectively.The results showed that the incidences of pregnancy induced hypertension(PIH).serious vomiting and anemia during pregnancy.sponta- neous abortion and low birth weight in exposed group were significantly higher than those of control group.Lo- gistic regression model analysis indicated that there were associations between exposure to the mixture and PIH. spontaneous abortion or low birth weight.The concentrations of benzene,toluene and xylene in work places were close to MAC or exceeding 1-2 folds of MAC.