摘要
对57例烧伤面积30%以上病人进行系统的前瞻性观察,结果表明:烧伤后很早即有心肌损害,是心功能降低和衰竭的重要原因;烧伤后呼吸衰竭可分为三种类型、各类型的主要病因不同;血浆和脏器组织血栓素/前列环素失衡在多脏器衰竭(MOF)发生和发展中起重要作用,也是脏器损害和MOF主要影响因素(吸入性损伤、休克、全身性感染)病理生理变化的重要原因。
A prospective study was carried out on 57 patients with total burned surface area (TBSA) over 30%. It was found that myocardial damage occurred early postburn, which was one of the major causes of cardiac dysfunction and failure. The postburn respiratory failure (RF)might be classified into three patterns. The etiology of each pattern varied. The imbalance between thromboxane and prostacyclin in plasma and visceral tissues played important roles in the genesis and development of postburn MOF as well as the causes of pathophysiological alterations in the main factors (including inhalation injury, severe shock and systemic infection) which contributed to occurrence of visceral damage and MOF.
