摘要
Wistar大鼠35只,背部两侧皮肤各做纵行切口,分别等间距缝合。一侧缝合后即行激光焊接,术后24小时拆除缝线,另一侧常规缝合对照。在术后不同时间进行切口的生物力学测试,同时进行切口愈合的组织学观察。结果发现:激光侧皮肤切口炎症反应轻,瘢痕不明显,3天内,平均最大抗张强度明显高于缝合侧(P<0.05)。因此,激光焊接皮肤切口对整形外科可望有临床推广应用价值。
Incisions in 35 rats were performed on the back bilaterally. Both incisions were sutured by hand with threads at equal interval. One of the incisions immediately welded by laser after suture, the others as follow, when 24 hours after suture, the stiches of the laser welded incisions were removed. The maximal strength force and histology of the bilateral incisions were measured and examied respectively at 1, 3, 7 and 14 days after the operation. The results showed: there was obvioussely significant difference of the strength force within 3 days between the two incisions. There was slightly inflammatory reactions, no sar and ideal healing in laser welded incisions.
基金
国家自然科学基金
