肺癌患者血清抗巨噬细胞抗体的检测(附65例病例分析)

DETERMINATION OF SERUM ANTI-MACROPHAGE ANTIBODY IN PATIENTS WITH LUNG CANCER (A REPORT OF 65 CASES)

用SPA花环试验对65例肺癌、44例非癌肺部疾病患者和59例健康人血清中抗Mφ抗体进行了检测,结果显示抗Mφ抗体的阳性率分别为44.6％、13.6％和3.4％。肺癌患者血清中抗Mφ抗体水平显著高于其它两组(p<0.05)。在组织学类型不同的肺癌组中,血清CEA阳性率最高的腺癌组抗Mφ抗体阳性率最低。

Serum anti-macrophage antibody levels of 65 patients with lung cancer; 44 patients wtth lung benign diseases and 59 healthy subjects have been measured by staphylococal protein A rosette test. Positive rates of the anti-macrophage antibody in 3 groups were 44.6％, 13.6％ and 3.4％, respectively. A significant difference (p<0.05) existed between the lung cancer group and other groups. Serum anti-macrophage antibody level is related to histological type of the lung cancer. Positive rate of serum anti-macrophage antibody was lowest in the patients with adenocarcinoma of the lung.