摘要
本文采用呋喃氟脲嘧啶(FT-207)与增效减毒剂左旋咪唑(LMS)伍用来提高FT-207的疗效。结果伍用对小鼠S-180肉瘤的抑制作用与LMS的剂量有关,以低剂量的LMS(1mg/kg)抑瘤最佳,并能拮抗FT-207所致小鼠白细胞下降,增加小鼠胸腺和脾脏重量,促进小鼠腹腔内巨噬细胞吞噬功能,提高小鼠脾脏中NK细胞活性。
The article reports that Ftorafur (FT-207) combined Levamisli(LMS) can incr-iease the curative effect of FT-207. The results shows that FT-207 Combined LMS onnhibition function of S180 sarcoma in mice concerns with the dosage of LMS. Low-dose LMS (1mg/kg) can increase the number of white blood cells, the weight ofthymus and spleen, the phagocytosis of macrophage and the activity of spleen NKcells in mice.
出处
《肿瘤》
CAS
CSCD
北大核心
1993年第3期143-145,共3页
Tumor
