^(60)Co腔内后装合并微波加热治疗子宫颈癌的近期疗效观察

Preliminary Results of Carcinoma of Uterine Cervix Treated with ^(60)Co Intracavitary Afterloading Combined with Hyperthermia

自1990年11月～1992年6月,20例宫颈癌采用^(60)Co后装腔内放疗,A点剂量500cGy,照射后1小时给微波加热,43℃左右,加热30min,每周2次。17例宫颈癌仅作^(60)Co后装腔内放疗。于治疗前及3次治疗后均记录肿瘤休积、病理变化及流式细胞检测。结果放疗效疗组肿瘤缩小、病理改变,异倍体转变成二倍体者,均较放疗组高。作者认为放疗合并热疗可能提高宫颈癌的疗效。

From Nov., 1990 to June, 1992,20 patients with carcinoma of uterine cervix weretreated by ～(60)Co intracavitary afterloading combined with hyperthermia. Dose of Apoint was 500cGY each time, one hour after radiation, patients were treated with 30min of microwave hyperthermia twice a week. The temperature of central tumor corewas about 43℃,17 cases were treated by ～(60)Co intracavitary afterloading only. Tumorvolume, histologic change and FCM study were detected before and after therapy.The results showed that the effects with the heat-treated patients were superior tothose of patients treated with radiation alone. From above study, the authors believethat the intracavitary afterloading combined with hyperthermia may improve theeffect of advanced carcinoma of uterine cervix.