501例无精、少精子症细胞遗传学研究

CYTOGENETIC STUDIES IN 501 CASES OF ASP ERMIA AND OLIGOSPERMIN SUFFERER

本文对501例无精、少精子症患者进行染色体分析,发现异常核型145例,其中X染色体数目异常81例,易位、倒位11例,Y染色体结构异常49例,XX男性2例,额外小染色体1例,总的染色体异常率为28.94%。本文还分析了核型与表型的关系,并从细胞遗传学的角度对无精。

501 cases of aspermia and oligospermia were cytogenetically studied. The incidence of chromosomal abnormalities was 28.94%. Among them, incidence of chromosomal abnormalities of aspermia (40.49%) was higher than that of oligospermia (13.83%) . The rsport also showed that numeral abnormalities of X chromosome were important factor of aspermia and structural abnormalities of Y chromosome were irnpertent factor of oligospermia