摘要
蛤蚧乙醇提取液可使18月龄大鼠子宫卵巢重量增加22.73%、血中雌二醇(E_2)水平增高170.38%和卵泡刺激素(FSH)水平降低19.91%,与对照组相比均有显著差异(分别P<0.05或p<0.01)。在动情周期的不同阶段,上述三指标的变化率也有所差异。作者认为,实验结果提示蛤蚧提取液具有雌激素样作用,能直接作用于外周性器官组织,引起卵巢分泌E_2水平增高。
The changes in the weight of rat's sex organ and serum estrogen (E2) and follicle stimulating hormone (FSH) levels after injecting the elhanol extract of G-ecko (a kind of Chinese Medicinal Herb) were observed. The results indicate that G.gecko may increase the weight of rat's ovary and uterus (P<C0.05), and significantly elevate the level of Ei(P<0.01) and decrease the level of FSH(P<0.05). When the G.gccko extract was given at the different phases in oestrous cycle, the changes of the three items mentioned above were different. We consider that G, gecko may directly , act on the sex organs, promote the ovary to secrete more E3 and in turn product a negative feedback to depress the FSH secretion
出处
《重庆医科大学学报》
CAS
CSCD
1993年第1期19-21,共3页
Journal of Chongqing Medical University
关键词
蛤蚧
卵巢
子宫
大鼠
雌激素
药理
G.gecko
Estrogen, Follicle Stimulating Hormone
Oestrous Cycle)Ovary. Uterus
Rat