溃疡病外科治疗术式对胆汁返流的影响

INFLUENCE OF SURGICAL PROCEDURES FOR TREATMENT OF ULCER DISEASE ON BILE REFLUX

本文检查了39例消化性溃疡患者手术前后的空腹胃液胆酸浓度、pH及胃内细菌变化,并对术后1年的患者进行胃镜检查,发现B-Ⅱ组、B-I组及SV+A组术后胃液胆酸浓度、pH及细菌量均显著高于HSV组,胃镜所见肠胃返流程度亦显著高于HSV组(P<0.05),胃液PH与胃液胆酸浓度是显著正相关(r=0.351,P<0.05),提示HSV确能防止胆汁返流,使残胃胃内环境保持相对稳定.

The concentrations of bile acids. PH and total bacterial counts in the gastric juice were measured among 39 patients with peptic ulcer before and after operation. All of them were studied by endoscopy one year postoperatively. The results showed that the fasting gastric bile acids concentrations. PH and total bacterial counts in B- Ⅱ group, B- I group and SV+A group were significantly higher than in HSV group following surgery . The extents of bile reflux were more severe in B- I group ,B- I group and SV+A goup than in HSV group (p<0. 05). A possitive relationship was found between gastric PH and bile acids concentrations (r = 0. 351,p<0. 05). It is demostrated that HSV can really prevent the bile reflux effectively and keep the gastric physiology in a relatively stable status.