间接检眼镜不同光照时间对灰兔视网膜电流图a波和b波的影响

The Effects of A-wave and B-wave of Electroretinogram in the Retina of Gray Rabbits by Indirect: Ophthalmoscopy at Different Time of Light Exposure

为探讨间接检眼镜医源性光损伤对灰兔视网膜电图(ERG)的影响,12只24眼北京青紫兰灰兔进行了视网膜光损伤试验,每眼分别接受间接检眼镜光照(视网膜照度为390.7mW/cm^2),设光照1小时,30分钟和15分钟三个观察组,与照光前比较。照光后30分钟,1、3、6小时和1、7、24天,重复测量ERG的a波和b波。采用美国SAS统计分析软件,对资料进行具有重复测量的双因素的设计资料的方差分析。结果表明,光照1小时组和30min组,于光照后30分钟至1小小时εRG的a波和b波振幅下降幅度最大(P<0.01)光照15min组也受到一定程度影响。

IN order to study the changes of electroretinogram in photic injury of the retina, 12 rabbits (24 eyes) underwent experiment of light damage to the retina. All the eyes were randomly divided into three groups, photic injury for 1 h group, 30 min group and 15 min group. The eyes were exposured to the light of indirect ophthalmoscopy (390. 7mw/cm^2 at the retina). Three groups were all examined before exposure and at the 30 min, 1, 6 h and on the 1, 7, and 14 day after exposure. The results demonstrated that the amplitude of respectively a-wave and b-wave in the darkadapted ERG responses at the 1h group and 30 min group decreased more markedty than 15 min group. (P<0.01)