酸中毒和微循环障碍在SMAO休克发病机制中的作用

EFFECT OF THE CHANGES IN ACIDOSIS AND MIC ROCIRCULATION DISORDER ON THE MECHANISM OF SUPERIOR MESENTERIC ARTERY OCCLUSION SHOCK

通过夹闭成年大耳白兔肠系膜上动脉(SMA)60min 后松夹,复制肠系膜上动脉闭塞性休克(SMAO 休克),以血压下降50%为指针。休克组兔颈动脉血压下降,血气的变化为:pH 值降低、PaCO_2降低、B、E、负值增大,微循环障碍。对照组,上述指标的数值前后变化不显著,结果表明:酸中毒和微循环障碍,在 SMAO

The superior mesenteric artery occlusion shock model was induced by clamping the superior mesenteric artery(SMA)for 60 minutes then relea- sing the artery clamp.Shock was considerd if the blood pressure at 120 minutes after releasing the artery clamp reduced to 50% of that before clamping SMA.In the shock group at 120 minutes after releasing the arte- ry blood pressure decreased,the changes of blood gas were.pH decreased paco_2 reduced B、E increased,microcirculation disorder developed.The difference was significant(P<0.01). In the control group no significant changes occurred in the above index. This result showed that acidosis and microcirculation disorder pla- yed an important part in inducing SMAO Shock.