摘要
本文采用反相高效液相色谱紫外检测尿中多胺的含量。选择正常健康 36人作为对照组,测得尿中多胺总量平均值为2.15±0.44(mg/24h),多胺与肌酐总量比值为1.85±0.54。另外对各种恶性肿瘤102例作了测定,多胺总量平均值为4.32±0.34(mg/24h)。多胺与肌酐总量比值3、67±0.35,有显著性差异P<0.01。观察组经有效治疗后多胺下降,复发时多胺又升高。
The content of polyamines in urine was defermined by reversed-phase highperformance liguid chromat. graphic ultra-viclef detetor. Thirtysix health personswere selected for confrol and the polyamine examined with the average was 2. 15±0. 44mg/24h The ratio of polyamine and creafinine of urine was 1. 85±0.54mg/24h.Polgamine of 102 patients with various malignant tumors were examined with theaverage of 4.32±0. 34mg/24h The difference was more significant (P<0. 01). Thepolyaminedecreased after effective freatment but increased again when relapse.