15例新生儿深部霉菌感染临床病理分析

Clinicopathologic Study on 15 Cases of Neonatal Deep Mycosis Infection

分析新生儿深部真菌感染15例尸检的临床病理特点。其中白色念珠菌感染11例,毛霉菌感染6例,曲霉菌病2例(6例为双重感染)。全部病例胸腺均呈重度萎缩。重点分析4例毛霉菌引起的原发性真菌病,证实毛霉菌可以通过脐部创口引起肝坏死,进而向它处播散。并讨论了其它常见致病因素及真菌病诊断中应注意的事项。

The clinicopathological characteris-tics of 15 cases of neonatal deep mycosis infec-tion were studied.There are 11 cases of candidi-asis,6 cases mucormycosis and 2 cases of as-pergillosis.The thymuses of all the cases showedatrpohy of sever degree.We focused our analy-sis on 4 cases of primary mycosis caused by mu-cormyocsis.The data demonstrated that the mu-cormycosis could cause hepatonecrosis throughthe opening of their umbilicus and spreading toother parts of the body.Other common patho-genic factors and diagnosis of mycosis were dis-cussed.