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用Ames试验和SOS显色法研究水源水有机提取物的遗传毒性 被引量:12

STUDIES THE GENOTOXICITIES OF ORGANIC EXTRACTSFROM THE SOURCE WATER WITH AMES TEST AND SOSCHROMOTEST
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摘要 本文应用Ames试验和SOS显色法2个细菌测试系统研究了广州南部流域某些河段水中有机物的遗传毒性.13个水样中,4个可诱导鼠伤寒沙门氏菌组氨酸缺陷型菌株的回复突变;6个可诱导大肠杆菌的SOS反应;2个水样在2个测试系统中均有诱导作用.结果还表明;采集的水样量及受试物的配制对试验结果有显著影响;在SOS显色法中,uvrA菌株和uvr+菌株对相同水样有不同反应。 In a survey of a new source of water supply,the genotoxicities of organic ex-tracts of water samples taken from rivers in south areas of Guagzhou were studied withSOS Chromotest and Ames Test. Of all the 13 sampls tested,6 induced SOS rection ofE.coli tester strain PQ37,4 induced reversion of Salmonella tester strains, 2 showedpositive reaction in both bactcterial testing systems The present studies showed that theamountof the water samples and the way the samples were made affected the results of thegenotoxicity studies and that in SOS chromotes uvrA strain and、uvr strain differed in theirreaction to the same water samples.
出处 《癌变.畸变.突变》 CAS CSCD 1994年第1期25-31,共7页 Carcinogenesis,Teratogenesis & Mutagenesis
关键词 AMES试验 SOS显色 水质 遗传毒性 Ames test SOS chromotest source water quality organic extracts mutagen
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  • 1陆寿珍,细胞生物学杂志,1989年,11卷,3期,131页
  • 2陈中孚,微生物学报,1988年,28卷,4期,313页

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