摘要
本文以姊妹染色体交换（ＳＣＥ）和微核（ＭＮ）为指标，评价了中药丹参和半枝莲对丝裂霉素Ｃ（ＭＭｃ）诱发小鼠遗传物质损伤的影响，证实了两种中药本身并无诱变作用，提出了丹参，半枝莲具有抗ＭＭＣ诱发遗传物质损伤的作用。
By using sister chromatid exchange(SCE)and mieronucleus(MN)as indexes,the
protective effects of Salvia miltiorrhiza and Scutellaria on genetic damage induced by MMC
was studied in Kunming mice strain.Results showed that the two Chinese medieines
themselves can not induce genetic damages but can significantly decrease SCE and MN
frequencies induced by MMC,respectively(P<0.01).The results indicated the Chinese medicines
could be anti-mut-agenesis.
出处
《癌变．畸变．突变》
CAS
CSCD
1994年第6期44-47,共4页
Carcinogenesis,Teratogenesis & Mutagenesis
关键词
丹参
半枝莲
微核
SCE
中药
抗癌药
Salvia miltiorrhiza
Scutellaria
Micronucleus
SCE
Genetic
damage
