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胃粘膜癌前病变细胞的核和核仁组成区嗜银蛋白图像分析 被引量:1

IMAGE ANALYSIS OF NUCLEAR AND AGNOR IN CELLS OF PRECANCEROUS LESIONS OF THE STOMACH MUCOSA
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摘要 以银染方法,用VDP一1750型自动图像分析仪(美国VICOM公司),对125例胃粘膜细胞的核和核仁组成区嗜银蛋白,进行20项几何学参数,构造参数测量。结果经多元判别分析,选择判别作用较大的参数组成判别函数,建立判别模式,取得了与原诊断较好的正确符合率,其回代正确率高达93.6%;刀切法正确率达90A%。 With VDP-1750 automatic image analysis system(VICOM CO,U.S.A·),the geometric and texture features of epithelial cell nulear and nucleolar organizerregions were measured from precancerous lesions of 125 cases of stomach mucosa stainedby colloid silver technique. The features Which have greatest contri bution to diagnosiswere selected by step forward discrimination ,then a discriminant functio was establis-hed on these features Computer classification have a good result when compared withthe original diagnosis, the correct rate was 93.6% in replace mathod,and 90.4% by Jack -knife method.
出处 《癌症》 SCIE CAS CSCD 北大核心 1994年第2期107-111,155,共6页 Chinese Journal of Cancer
关键词 胃粘膜 癌前病变 AGNOR染色 Stomach mucosa Precancerous lesions Nucleolar organizer regiom Lmage analysis
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  • 1D. Ploton,M. Menager,P. Jeannesson,G. Himber,F. Pigeon,J. J. Adnet. Improvement in the staining and in the visualization of the argyrophilic proteins of the nucleolar organizer region at the optical level[J] 1986,The Histochemical Journal(1):5~14
  • 2W. M. Howell,D. A. Black. Controlled silver-staining of nucleolus organizer regions with a protective colloidal developer: a 1-step method[J] 1980,Experientia(8):1014~1015
  • 3Carll Goodpasture,Stephen E. Bloom. Visualization of nucleolar organizer regions in mammalian chromosomes using silver staining[J] 1975,Chromosoma(1):37~50

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