摘要
以对硝基苯甲酸为原料,经氯化后,被β—氨基丙酸取代,得到对硝基苯甲酰—β—氨基丙酸,再经还原、重氮化后,与水杨酸偶合,合成了抗溃疡性结肠炎新药—5—〔[4[(β-羧乙基)甲酰氨]苯]偶氮基〕水杨酸(Balsalazide),并做了红外光谱鉴定。
Anti inflammatory Agent 5 [4 [(2 Carboxyethyl)Carbamoyl]phenyl]azo Salicylic Acid (Balsalazide) have been Synthesized from P nitrobenzoid Acid and Testified By IR. The Synthesis Consists of four steps.