小儿钩端螺旋体病神经系统并发症的探讨

CLINICAL CHARACTERISTICS AND PATHOGENESIS RESEARCHABOUT NERVOUS SYSTEM COMPLICATIONS OF LEPTOSPIROSIS

本文报道４６例小儿钩端螺旋体病神经系统并发症的临床特点，有脑损害的３６例以中枢性瘫痪或惊厥为主要表现，有脊髓损害的６例表现为下肢运动障碍、反射亢进、大小便失禁，有颅神经损害的４例以面神经受损为主．认为钩端螺旋体神经系统并发症的发病机制是钩端螺旋体或钧端螺旋体Ｌ型慢性感染和感染后免疫反应共同作用导致神经系统损害．

This paper reported the clinical characteristics of 46 cases with leptospirosis nervotussystem complications.The characteristics of the 36 patients with brain injury were centric paraly-sis or convulsions.Lower limbs paralysis,tendon hyperreflexia,incontinence of faeces and urineoccured in 6 patients with spinal cord injury.Facial nerve paralysis was the main manifestation in14 patients with cranial nerves injury. It suggested that leptospirosis nervous system complicationwas caused by the chronic infection of leptospira or leptospira L-forms and the postinfection im-munity.