16ξ－溴－3－乙酰氧基－17，17－乙二氧撑－1，3，5（10）－雌三烯的制备及其构型的研究

Preparation of 16ξ-Bromo-17, 17-ethylenedioxyestra-1, 3, 5 (10)-trien-3-ol-acetate and Study on Its Configuration

以３－乙酰氧基－１７，１７－乙二氧撑－１，３，５（１０）－雌三烯为原料制备１６ξ－溴－３－乙酰氧基－１７，１７－乙二氧撑－１，３，５（１０）－雌三烯的反应中，采用不同反应条件，得到２种化合物．通过物理方法和化学方法，证明这２种化合物为立体异构体，并确定了它们的构型．

wo compounds were obtained in preparing 16ξ-bromo-17, 17-ethylene dioxyestra-1, 3, 5 (10)-trien-3-of-acetate from 17, 17-ethytenedioxyestra-1, 3, 5(10)-trien-3 of-acetate in different conditions, and by using physical and chemical methods, these two compounds were proved as stereoisomers with same formula and structure. Their configu rations were also determined.