富硒营养粉对人工缺硒小鼠免疫、衰老、疲劳等生理指标的影响

The Effect of the Selenium-Rich Nutrient Power on the Immunity,Aging and Fatigue of Selenium-Dificient of Mice

以中国农业科学院提供的低硒饲料（０．０２×１０￣（－６）），喂养ＢＡＬＢ／Ｃ小鼠作为缺硒动物模型，采用富硒营养粉和亚硒酸钠溶液，以每只小鼠每ｄ２．５μｇ元素硒作为补充，７０ｄ后发现：富硒营养粉和亚硒酸钠对小鼠全脑Ｂ型单胺氧化酶活性无显著影响（Ｐ＞０．０５）；前者使肝脏超氧化物歧化酶活性增高３６．１％（Ｐ＜０．０５），后者对其无显著影响（Ｐ＞０．０５）；两者均极显著地（Ｐ＜０．０１）提高巨噬细胞吞噬率（５９．８％和７１％）和吞噬指数（６８．５％和６５．１％）；提高溶血素含量，前者为６５％（Ｐ＜０．０１），后者为４１．３％（Ｐ＜０．０５）；富硒营养粉能使运动后小鼠血乳酸含量迅速下降３１．８％（Ｐ＜０．０１）。

Each BALB/C mouse was fed each day with 2.5 microgram of selenium element inthe form of low-selenium feed(0.02×10￣(-6))provided by the Chinese Academy of agricultural Sci-ences.The feed is a mixture of selenium-rich nutrient power and selenite solution.After 70 days themice did not show obvious effect on the activity of B-type monoamine oxidase of the mouse brain(P>0.05).But the nutrient power increased the activity of superoxidase dismutase of the mice liv-er by 36.1 percent(P<0. 05)while the selenite solution did not show obvious effect(P>0.05 ) Both showed marked effect on the increase of macrophage phagocytic percentage (59.8 percentand 71 percent respectively)and phagocytic index (68.5 percent and 65.1 percent respectively)The nutrient power increased the erythrolysin content by 65 percent (P<0.01)and the selenitesolution increased it by 41.3 percent (P<0.05). The selenium-rich power can reduce the contentof bloed lactic acid in the mice after physical exertion quickly by 31.8 percent(P<0.01).[