凝集素ConA对红细胞小变形及其在C＝0轨道取向的影响

The Effects of Agglutinin ConA on Erytherocyte small Deformation and its Orientation in Orbit C=0

作者用激光衍射法研究了凝集素ＣｏｎＡ对红细胞在低粘度低剪切率流场中小变形及其在Ｃ＝０轨道取向的影响。结果表明，在各种低剪切率γ下均有ＣｏｎＡ对红细胞作用的量越大，红细胞变形指数ＤＩ和取向指数ＯＩ就越小。这可能是由于ＣｏｎＡ与红细胞膜上的受体结合，改变了细胞膜的成分、红细胞膜刚性增强、粘弹性下降的结果。

The effects of agglutinin ConA on erytherocyte small deformation and its orientation in orbit C=0 in the low shear flow field of low viscosity were studied by means of ektacytometry.The results show that at any low shear rate γ,the more the effect of ConA on erytherocyte,the smaller the erytherocyte deformation index DI and orientation index OI.It might due to the combination of ConA and the receptor on the erytherocyte membrane,which result in the increasing of membrane rigidity and decreasing of membrane viscoelasticity.