抑郁症病人视觉诱发电位的对照研究

A COMPARATIVE STUDY OF VEPINDEPRES SIVES

对４０例抑郁症病人（内源性抑郁１２例、非内源性抑郁２８例）与３８例正常人进行了视觉诱发电位的对照研究。结果表明，抑郁症组与正常组比较，Ｐ１与Ｎ２潜伏期明显缩短。非内源性与内源性抑郁及正常人三组间比较：（１）非内源性抑郁与正常人比较Ｐ１缩短；（２）内源性抑郁与正常人比较Ｎ１与Ｐ２明显缩短；（３）非内源性与内源性抑郁比较未见显著性差异，仅表现为内源性抑郁Ｐ２有缩短趋势。此研究反映了抑郁症病人与正常人之间及抑郁症各亚型之间存在不同的脑电生理方面特征。

Acomparative study on vlsual evoked potentials (VEP) was carried out on 40 depressive cases(12cases wirh endogenous and 28 cases with non-endogenous depression)and 38 controls The results indi-cated that the latencies of Pl and N2 in the depressive patients were significantly shorter than those of the controls,It was found in comparison among non- endogenous,endogenous depressives,and co-ntrols that:(1) Pl latency was significantly shorter in non- endogenous than in controls;(2)compared with normal controls,there werd obviously shortened latencies of both Nl and P2;(3)Although there was no sign ificant differen c between endogenous and non- endogenous depressives in VEP,P2 showed tend ency to shorten atcncy in endognohsdeprssive,This study reflected different characterististics of visual evokedpotentials amongdepressives,normal controls, and the subtypes of depressives.