氟中毒对家蚕幼虫中肠组织糖原分解代谢调节的影响

EFFECT OF FLUORIDE POISONINC ON REGULATION OF GLYCOGEN CATABOLISM IN LARVAL MIDGUTS OF SILDWORM,BOMBYX MORI

用酶偶合系统测定了氟中毒对家蚕幼虫中肠组织糖原磷酸化酶活性的影响，其结果人氟中毒使中肠糖原磷酸化酶ａ型和ｂ型的活性均明显下降，特别是ｂ型的活性下降幅度较大。由此时以认为，氟中毒抑制了家蚕幼虫中肠组织内糖的分解代谢，使细胞的能量供应减少。

Phosphory lase activity was determined by using an enzyme coupled system.The relative activity of phosphorylase a and b in the crude extracts of silkworm larval midguts was decreased by feeding NaF. And the phosphorylase b activity lowered more remarkably than that of a.This indicated that the glycogonolysis and carbohydrate me-tabolization in the larval midgut tissues poisoned by fluoride were inhibited and the ener-gy supplement in the cell of larval midgut was decreased.