重度妊娠高血压综合征合并DIC21例临床分析

CLINICAL ANALYSIS OF 21 CASES OF SEVERE PRECNANCY─INDUCED HYPERTENSON COMPLICATED BY DIC

本组２９８例重度妊高征患者中有２１例并发ＤＩＣ（占７．０５％），其中农民１４例（１４／２１）。从孕期来看，晚期孕妇发病较多（１７／２１）；从产次来看，初产妇发病较多（１３／２１）；从诱因来看，胎盘早剥者较多（５／２１），但无诱因发生ＤＩＣ者亦不少（５／２１）；ＤＩＣ合并肾衰酸中者较多（１１／２１）。在２１例患者中共死亡７例，主要死因为休克；在２１例患者中共治愈１４例，主要应用硫酸镁治疗妊高征、终止妊娠、纠正酸中毒、肝素抗凝等治疗措施。作者体会，根据妊高征并发ＤＩＣ的特点早期作出诊断和及时进行治疗，大部分患者预后良好。

Pregnancy─induced hypertension complicated by DIC was diagnosed in 21 of 298 patients with severe pregnancy─induced hypertension. Among them , latepregnant women and premiparae accounted for 80. 95%(17/21) and 61.90%(13/21)respectively. In the prediposing cause, DIC was induced by premature separation ofplacenta in 5 cases(5/21),and no precipitating factor was found in the other,5 cases.There were 11 cases of DIC accompanied by renal failure─induced acidosis. Among the 21 patients , 14 were cured completely and 7 died of shock. The main therapies were treatment of the severe pregnancy─induced hypertension with magnesium sulfate,termination of pregnancy,correction of acldosis ,prevention of blood coagulation withheparin , etc.lt is favourable for prognosis of the disese to make diagnosis as early aspossible and to perform treatment without delay.