前列腺特异抗原测定临床意义的初步评价

Comment clinical significance of serum prostate specific antigen

我们用北京医科大学泌尿外科研究所提供的药盒，并采用他们创立的生物素－亲和素酶联免疫法进行ＰＳＡ测定，总病例数１４８例，其中前列腺癌１３例，前列腺增生症５５例，前列腺炎２７例，其他无前列腺增生疾病的患者２９例，女性病人２４例。测定结果表明，前列腺癌患者ＰＳＡ含量明显升高，分期越晚ＰＳＡ越高，前列腺增生症患者有一部分ＰＳＡ在一定范围内有所增高，其他病人及女性病人ＰＳＡ均正常。我们认为ＰＳＡ是诊断较为早期前列腺癌的灵敏的标记物。

We measured serum PSA by BA-ELISA method in 148 patients.Among them,13 cases were prostatic cancer,55 BPH,27 prostatitis,53 other case.The levels of PSA in prostatic cancer were obriously higher than than BPH and other cases(P<0.005).We believe that serum PSA level is valuable for the early dignosis of prostatic cancer