摘要
本文报告了1992年4月~1992年12月在我院呼吸病房住院诊断为下呼吸道感染的203例,分离出致病菌135株,其中莫拉氏菌30株,占22.2%,仅次于绿脓杆菌(23.7%),居第二位。30例莫拉氏菌感染中,21例有原发疾病,其中18例为COPD。对30株莫拉氏菌进行药敏感试验,结果表明其对麦迪霉素、红霉素、青霉素、氨苄青霉素、先锋V、磺苄青霉素的耐药率达50%以上。对头孢噻肟钠、庆大霉素的耐药率分别为33.3%与40%。而对优立新(氨苄青霉素/青霉烷砜)、噻比达(先锋必/青霉烷砜)、环丙沙星、头孢哌酮和丁胺卡那的耐药率<20%。
We have retrospectively studied 203 cases with lower respiratory tract infections administered from April 1992 to December 1992.135 strains of bacterial organisms were isolated from sputum or BALF, among them 30 strains were Moraxella catarrhalis(22.2%) that was just less than the leading strain pseudomouas aeruginosa. Amony 30 cases of Moraxella catarrhalis respiratory infection,21 patients had an underlying disease with 18 cases of chronic obstructive pulmonary disease. The antimicrobial susceptibility of 30 clinical strains was tested. The rate of resistance to midecamycin, kitasamycin,erythromycin, penicillin, ampicillin was more than 50 percent,to ceftizoxime,gentamicin were 33.3 percent and 40 percent to umasyn, sulperazone,ciprozloxacin,cefoperazone,amikacin was less than 20 percent.