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硒代半胱氨酸(selenocysteine):密码表中第二十一个氨基酸? 被引量:1

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摘要 已知所有的氨基酸中,只有遗传密码表内的20种基本氨基酸才能在核糖体中直接掺入肽链;但最近发现于原核、真核生物中的含硒酶里的硒代半胱氨酸(Se-Cys)似亦有此特点。生化、遗传实验均表明Se-Cys对应于终止密码子UGA;相应的tRNA(95bp)基因已经找到。但其转录产物上所携的Se-Cys很可能由原先携带着的Ser经O-磷酰Ser而来。上述发现显示了UGA作为有义密码子的保守性:也许它正处于从有义密码子变为无义密码子的进化过程中。
出处 《生物化学与生物物理进展》 SCIE CAS CSCD 北大核心 1989年第5期326-327,共2页 Progress In Biochemistry and Biophysics
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