藏族与汉族脑中风高危人群8种元素的比较

Comparison of Eight Elements in Stroke-prone Patients of Tibetan and Han Nationality

应用原子吸收和火焰光谱分析法，检测了藏族和汉族脑中风高危人群头发和血清微量元素Ｚｎ、Ｃｕ、Ｆｅ、Ｍｎ和常量元素Ｋ、Ｎａ、Ｃａ、Ｍｇ的含量，经统计学处理，探讨了８种元素与血压（ＢＰ）、生化指标的关系。结果发现藏族的Ｎａ、Ｍｎ、Ｎａ／Ｋ明显高于汉族和对照组，而Ｋ、Ｃａ／Ｍｇ则低于汉族和对照组。Ｎａ／Ｋ、Ｆｅ、Ｍｇ、Ｍｎ与ＢＰ；Ｚｎ，Ｚｎ／Ｃｕ与红细胞压积（ＨＣＴ）、胆固醇（Ｃｈ）、甘油三酯（ＴＧ）、低密度脂蛋白（ＬＤＬ－ｃｈ）、极低密度脂蛋白（ＶＬＤＬ－ｃｈ）、Ｃ肽；Ｆｅ与ＨＣＴ均呈正相关，Ｃａ／Ｍｇ与ＢＰ呈负相关。提示：藏族的高血压、脑中风发病率高，与Ｍｎ、Ｆｅ、Ｎａ／Ｋ较高，与Ｃａ／Ｍｇ较低有密切的关系。

The serum and hair contents of trace elements Zn, Cu, Fe, Mn, and major elements K,Na, Ca, Mg in stroke-prone patients (SPP) of Tibetan and Han Nationality were determined with Atomic Abeorption Spectrophotometer and Flame Photometer. The data were analysed statistically,and the relationship between eight elements and blood pressure(BP), biochemical targets were studied. It was found that the contents of Na, Mn, and Na/K of the SPP in Tibetan were significantly higher than those in the Han Nationality and the control group, while K, Ca/Mg were significantly lower than those in the Han Nationality and the control group. There was a significant positive correlation between Na/K, Fe, Mg, Mn and BP, between Zn, Zn/Cu and HCT, Ch, TG,LDL-ch VLDL-ch, C-peptide, between Fe and HCT, while a significant negative correlation between Ca/Mg and BP. It is suggested that incidence and prevalence of HP and stroke in Tibetan is closely related to the higher contents of Mn, Fe, Na/K, and lower K, Ca, Ca/Mg.