精浆肉毒硷和α-糖苷酶的测定在男性学中的应用

MEASUREMENT OF CARNITINE AND α-GLUCOSIDASE LEVEL IN HUMAN SEMINAL PLASMA AND ITS SIGNIFICANCE IN DIAGNOSTIC ANDROLOGY

本文测定了80例无精症精浆肉毒碱,29例无精症精(?)α-糖苷酶,其值与正常生育力组存在明显差异。测定了12例明确诊断为严重睾丸病变引起的分泌性无精症,10例由排出障碍引起的阻塞性无精症,两者相比,差异十分明显,阻塞性无精症精浆肉毒碱低于100nmol/ml,因此100nmol/ml精浆肉毒碱可作为阻塞性无精症的诊断标准。测定90例精索静脉曲张不育症,精浆肉毒碱也有明显降低,表明附睾功能受到了影响,在用中西医结合方法治疗后,精浆肉毒碱上升,精子活动度改善。

Carnitine and α-glucosidase in human semen are of diagnostic value for epididymal function: in 90 patients with azoospermia, the mean value of carnitine concentration is 160.69±63.59 nM/ml, in 29 patients with azoospermia, the mean value of α-glucosidase concentration is 28.74±18.41 mIU/ml, showed a marked reduction in comparison with the normal group. Between the secretory and excretory azoospermia, the difference of semen carnitine was significant. In general, the mean value of semen carnitine in the excretory azoosparmia is lower than 100 mmol/ml. The mean value of semen carnitine in 90 cases of infertiles with varicocele was lower than that of the normal, indicating the presence of epididymal dysfunction. After the treatment with Chinese traditional medicine, the mean value of semen carnitine was increased.