鱼肝油酸避孕栓的临床疗效分析

THE CONTRACEPTIVE EFFECTIVENESS OF MORRHUIC ACID SUPPOSITORY

我们从1983年11月开始研究鱼肝油酸的杀精子作用,到1987年11月已用鱼肝油酸阴道栓剂避孕1,746人,共16,073妇女月。第一年1,354人,失败115例按生命表统计每100妇女粗累积失败率为10.1,按医嘱使用失败为55倒,每100妇女粗累积有效率为95.2,每100妇女粗累积续用率是73.7。此栓剂适用于育龄妇女各阶段年龄的避孕,尤其对新婚与更年期妇女有性交痛者,由于栓剂有润滑作用,可使疼痛减轻或消失。此外,避孕栓不含甾体激素,不会发生突破性出血或闭经,亦不影响乳汁分泌,可用于哺乳期避孕。本栓剂是一种简便、安全、有效的避孕方法,颇受多数妇女的欢迎。

The spermicidal effect of morrhuic acid has been studied. Up to now the morrhuic acid vaginal suppository for contraception has been used in 1,746 women, ie, 16,073 womanmonths of suppository use. There were 1,354 cases who were keeping on using morrhuic acid suppository for one year. The cumulative twelve month life table pregnancy rate was 10.1/100 women and the morrhuic acid suppository method pregnancy rate was 4.8/100 women, corresponding to effectiveness rate of 95.2 per 100 women. The gross cumulative termination rate per 100 women was 27.3 giving a continuation rate ef 72.7/100 women. This suppository is suitable for contraception of all fertile women especially to newly married, menopause or breast feeding women. Morrhuic acid vaginal suppository is a safe, simple, effective contraceptive method well accepted by women.