循环伏安法研究硝基药物的β-环糊精包含络合物

Study of the Drugs β-Cyclodextrin Inclusion Complexes by Cyclic Voltammetry

本文用悬汞电极循环伏安法,研究了甲硝唑、氯霉素、对硝基苯酚和对硝基苯甲酸等药物的伏安性质,用“电流法”测定了药物与β-CD生成包络物的K_f值,并讨论其作用及稳定性。

The cyclic voltammetric electroreduction behaviour of metronidazole chloram-phenicol etc. is studied on a hanging mercury drop electrode in 0. 1 mol/L KC1 Britton-Robin-son buffer medium. The formation constants(K_(f)) of drugs with β-CD are determined by using the 'electric current method'.