二烷基取代β-环糊精作毛细管气相色谱固定液的研究

Three Dialkylated-β-Cyclodextrins Used as Capillary Column Chromatographic Stationary Phase

合成了3种二烷基取代β-环糊精——七-(2,6-O-二丁基)-β-环糊精、七-(2,6-O-二戊基)-β-环糊精和七-(2,6-O-二己基)-β-环糊精,并用作毛细管气相色谱固定液,结果说明二丁基取代环糊精柱可涂渍成高效毛细管柱,对醇和酚类化合物异构体及一些对映异构体具有选择性分离能力。

Three dialkylated-β-cyclodextrins(CD), 2,6-O-dibutyl-β-CD, 2,6-O-dipentyl-β-CD and 2,6-O-dihexyl-β-CD, are synthesized and used as a selective stationary phase for the separation of isomeric compounds. The results show that 2,6-O-dibutyl-β-CD coated on fused silica capillary column is the best one for separating some place and chiral isomers.