β－环糊精对分子型体和离子型体2－萘酚及喹啉包结作用的研究

Study of the Inclusion of β-Cyclodextrin for 2-Naphthol and Quinoline in the Acidic or Basic Form

通过研究β－ＣＤ与离子型体２－萘酚和质子化喹啉混合物的核磁氢谱及β－ＣＤ与分子型体和离子型体２－萘酚包结物的解离常数后，认为β－ＣＤ易包结不带电荷和带负电荷的客体，不易包结带正电荷的客体。并且认为离子型体２－萘酚以轴向方式包结在β－ＣＤ空腔内，同时与β－ＣＤ细口端的伯羟基形成氢键。

It has been thought that it is easy for β-cyclodextrin (β-CD) to include the guest with negative charge or without charge, ahd not easy to include the guest with positive charge by our studying the 1H NMR spectra of 2-naphthol in the Basic form and quinoline in the acidic form,and the dissociation constant of β-CD with 2-naphthol in the acidic or basic form. It has been thought that the inclusion of the basic form 2-naphthol within the β-CD cavity is axial and a hydrogen bond will be formed between the primary hydroxyl group on β-CD and the R'O-species